"There has been an explosion of preclinical and clinical research leading to FDA approvals of immunotherapies that harness or enhance a patient's immune system to target tumors. However, despite promising clinical results, checkpoint blockade therapies can show intrinsic and acq…
Animal models in cancer drug discovery
Animal models in cancer drug discovery
Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community…
Animal models in cancer drug discovery
Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community…
Animal models in cancer drug discovery
Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community…
[Publisher-supplied data] Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such m…
Technological advances in manipulating the mouse genome has led to the development of sophisticated genetically-engineered models of human cancer that recapitulate many molecular, biologic and histologic features of human tumors. This book provides an overview of the design cons…
The carcinogenic mechanism of hepatobiliary and pancreatic tumors is poorly understood, making the development of rational treatment strategies difficult. The Syrian hamster is a unique animal for studying these neoplasms. This title explains various methods for the successful i…
This volume is essential for geneticists, molecular biologists, biochemists, and medical doctors interested in the use of mouse models in cancer research. Recent genome studies, together with refined genetic engineering techniques, have greatly increased the value of using mice …