Cancer immunotherapy principles and practice
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Now, it its second edition, this book summarizes the role of immune cells in tumor suppression and progression. It describes in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to canc…
This book reviews current immunotherapeutic strategies for gastrointestinal (GI) malignancies, including immune composition, immune checkpoint inhibitors, cell therapy, and peptide vaccines used to protect against esophageal, gastric, hepato-biliary, pancreatic and colorectal ca…
With the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially. Manag…
Despite advancements in our ability to diagnosis and treat cancer, cancer progression still occurs in many patients. Disease progression at sites other than the treated tumor remains an obstacle for improved patient outcomes. In-situ cancer vaccine strategies use immunotherapeut…
This book explains the immunology of organ-specific malignancies and discusses novel immunotherapy strategies for their treatment. Since the first, very successful edition of the book was published in 2015, a number of entirely new chapters have been included. The range of cance…
Introduction to antibody-drug conjugates (ADCs) / Ilona Pysz, Paul J.M. Jackson and David E. Thurston -- Design factors important for antibody-drug conjugate (ADC) payloads / John M. Lambert -- Use of molecular modelling techniques in antibody-drug conjugate (ADC) payload discov…
