The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of "Methods in Enzymology" along with Part C (volume 413) on Amylo…
Amyloid, prions, and other protein aggregates
This volume includes a core of methodologies to attack the unique experimental problems presented by protein misassembly. Emphasis is on human biology applications, the area in which there is the most interest, in which most of the work has already been done, and in which there …
The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part C (volume 413) on Amyloid…
Characterization of in vivo protein deposition Characterization of in vitro protein deposition Aggregate and precursor protein structure Cellular and organismic consequences of protein deposition.
Research on polyhedral manifolds often points to unexpected connections between very distinct aspects of Mathematics and Physics. In particular triangulated manifolds play quite a distinguished role in such settings as Riemann moduli space theory, strings and quantum gravity, to…
This rapid and concise presentation of the essential ideas and results of algebraic topology follows the axiomatic foundations pioneered by Eilenberg and Steenrod. The approach of the book is pragmatic: while most proofs are given, those that are particularly long or technical a…