The spread of cholera is always associated with contaminated food or water and this is the reason this disease has been endemic in developing countries for centuries due to their lack of proper sanitation facilities and poor or no infrastructure for sewage systems. Cholera can s…
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Aim: To assess the historical significance of the first Cholera epidemic in Britain. Part One. The Soil: describes the political, social and medical background to the 1831-2 period. Some subjects previously neglected by medical historians are dicussed. - Improvement Commissions …
This thesis examines the interplay between emotion and social memory in the historical narrative (re)formation of the Harrison Township Cholera Cemetery in the village of Lockbourne, Pickaway County, Ohio. The research agenda includes a contextualization and critical assessment …
Despite seasonal cholera outbreaks in Bangladesh, little is known about the relationship between environmental conditions and cholera cases. We seek to develop a predictive model for cholera outbreaks in Bangladesh based on environmental predictors. To do this, we estimate the c…
There is growing evidence that outbreaks of several water-related diseases are potentially predictable by using satellite derived macro-scale environmental variables. This research addresses cholera, which one of the most prevalent water-related infections in the tropical region…
Cholera, an acute diarrheal infectious disease caused by the bacterium Vibrio cholerae, displays a seasonal pattern that still remains poorly understood. Two epidemic peaks per year is the typical pattern in endemic areas in Bangladesh and former Bengal, with a decline in the su…
Vibrio cholerae O1 El Tor and O139 Bengal have caused cholera epidemics throughout Bangladesh and elsewhere in the world with a seasonal regularity. This has raised questions about whether clinical presentations of cholera caused by these two epidemic serogroups of V. cholerae r…
This dissertation examines cholera vaccination policy in a developing country context based on a combination of epidemiological and microeconomic data representing private demand for purchasing vaccinations, cost of illness, cost of vaccination, and herd protection impacts of va…
Prediction of water-borne diseases is a critical aspect especially for developing countries. The current study focuses on cholera since it is considered to be a continuous public health threat. Vibrio cholerae , causative agent of cholera, is an autochthonous bacterial inhabitan…
This thesis argues that in the second half of the 19th century, the Iraqi provinces of the Ottoman Empire constituted a frontier of imperial contestation between the Ottoman and British empires. The Ottoman Empire sought establish political hegemony over these far-flung province…
When evaluating the protective effect of a vaccine against infection, or vaccine efficacy (VE), it is important to consider whether the protection conferred on vaccinated individuals wanes with time. We consider the case that data are available on time to infection for both vacc…
Consisting of four articles, this thesis focuses on using time series analyses and theoretical modeling approaches to understand cholera dynamics and evolution in endemic regions. The first article develops a nonlinear statistical model with two related objectives: the reconstru…