"The aim of this unique volume is to help medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease. Written in a user-friendly step-by-step format, this work enables the researcher-with no background in statistics-to de…
"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development. Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry communit…
"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development. Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry communit…
Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first …
Why estimands are important -- Estimands and how to define them -- Strategies for dealing with intercurrent events -- Real world examples in choosing and specifying estimands -- Causal inference and estimands -- Putting the principles into practice -- Overview of estimators -- M…
Why estimands are important -- Estimands and how to define them -- Strategies for dealing with intercurrent events -- Real world examples in choosing and specifying estimands -- Causal inference and estimands -- Putting the principles into practice -- Overview of estimators -- M…
"The concepts of estimands, analyses (estimators) and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these topics. This book acts a practical guide to developing and implementing statistical analysis plans by explaining fundamental conce…
The concepts of estimands, analyses (estimators), and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these topics. This book acts as a practical guide to developing and implementing statistical analysis plans by explaining fundamental co…
The world is awash in data. This volume of data will continue to increase. In the pharmaceutical industry, much of this data explosion has happened around biomarker data. Great statisticians are needed to derive understanding from these data. This book will guide you as you begi…
The world is awash in data. This volume of data will continue to increase. In the pharmaceutical industry, much of this data explosion has happened around biomarker data. Great statisticians are needed to derive understanding from these data. This book will guide you as you begi…
Implementing CDISC using SAS: an end-to-end guide
by Holland, Chris, Shostak, Jack
fromITPro collection
For decades researchers and programmers have used SAS to analyze, summarize, and report clinical trial data. Now Chris Holland and Jack Shostak have written the first comprehensive book on applying clinical research data and metadata to the Clinical Data Interchange Standards Co…
"The proposed book will focus on practical issues in pharmaceutical/clinical research and development from both regulatory and scientific perspectives. The book will outline and clarify those issues that have been commonly misused in the subject area of regulatory science"--