Lipids are important for the structural and physiological functions of neuronal cell membranes. Alterations in their lipid composition may result in membrane dysfunction and subsequent neuronal deficits that characterise various disorders. This study focused on profiling lipids …
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Vitiligo is an idiopathic, non-contagious and often familial depigmentation disorder affecting both sexes equally. The mostly progressive and patchy loss of the inherited skin colour is not only a cosmetical problem, it has a profound impact on the patient's well-being. Stigmati…
To prove the post-natal depression model, the antidepressant sertraline, was assessed in rat mothers (n=14) divided into Prenatally Stressed (PS) and Non-Stressed (NS) groups. The data failed to support the hypothesis that ‘the progeny of 10mg of sertraline-treated PS mothers di…
Introduction: The current study examined the psychosocial predictors (Type D personality, anxiety, depression & social support) in patients following MI. It further assessed the influence of these psychosocial predictors on quality of life of MI patients. Methods: In this prospe…
The main aim of the current thesis was to evaluate a new psychological therapy service in Northern Ireland (NI), which is designed to treat adults with mild to moderate level mental health difficulties, primarily depression and anxiety. The particular mental health service model…
Background: Cardiac Rehabilitation (CR) has been shown to be effective in reducing mortality and morbidity in Coronary Heart Disease (CHD). There is a limited amount of research that evaluates the impact of menu-based CR, in patients with Acute Coronary Syndrome with Low Troponi…
Depression and social anxiety increase in prevalence during adolescence and are linked to long-term difficulties. The aetiology of increased onset of depression and social anxiety during adolescence is likely to be complex, encompassing social, biological and neuropsychological …
Currently there is limited research addressing the eating behaviours of preadolescent children, despite evidence suggesting that friends and peers may contribute to the developing eating attitudes and behaviours of children of this age. Eating behaviours in terms of this thesis …
Background: Mindfulness-based cognitive therapy (MBCT) is a promising new alternative to anti-depressant medication (Kuyken et al., 2015) and whilst some qualitative studies have explored participants' experiences of MBCT, none yet have explored experiences of participants who a…
Background: Juxtaposed with prevailing romantic myths surrounding images of UK veterinary practice are the reported alarming levels of psychological distress within the profession. Whilst an abundance of published quantitative studies report on the high proportional mortality ra…
Background: Intra-articular corticosteroid injections (IACI) are a commonly used treatment for painful knee osteoarthritis (OA). Response to treatment varies the reason for which is unclear. Further there are no data concerning the impact of accuracy of injection and psychologic…
This research projects deals with the question of whether the paintings of artists who have committed suicide is reflective of their mental states both in terms of content and form. It specifically attempts to answer whether the deterioration in mental state from a time of bette…
The primary aim of this thesis was to increase healthcare professionals' understanding surrounding the emotional distress of paediatric oncology patients prior to reaching five-year survivorship status, to inform resource allocation and evidence-based clinical interventions. Pap…
Prison self-injury rate accelerates at four times the rise in population” (The Howard League for Penal Reform; 2008a) The rise in self-harm figures in forensic settings in 2003 may largely be due to the improvement in the reporting of self-harm levels in prisons in December 2002…
Previous research has indicated that depression and thinking style (rumination versus distraction) interact to influence cognitive processing. Depressed ruminators produce more categoric autobiographical memories (AM) (i.e., a summary of repeated memories), and also demonstrate …
This thesis explores the histories of mild to moderate depression and the use of over the counter (OTC) St. John’s wort (St. John’s wort) during the 1990s. In doing so it not only investigates the diagnosis and definition of mental illnesses, it also raises questions about the i…
This dissertation focuses on conceptualizing psychosocial functioning in Malaysian adolescents, and understanding school factors related to these outcomes, so as to eventually assist school staff in developing techniques and programs in promoting positive youth development. Ther…
Depression is a multifactorial illness caused by interacting genetic and environmental risk factors. We created animal clones based on core symptoms of depression: lack of motivation, anhedonia and fatigue. We tested the effects of antidepressant treatments on the behavioral and…
The purpose of this study is to differentiate the neuropsychological differences between incarcerated veterans and non-incarcerated veterans. A literature search revealed a dearth of studies on the presence of traumatic brain injury (TBI), Posttraumatic Stress Disorder (PTSD) an…