[Publisher-supplied data] Homologous recombination is important in various aspects of DNA metabolism, including damage repair, replication, telomere maintenance, and meiosis, and yeast genetics has successfully provided a framework for the mechanism of homologous recombination. …
To understand the molecular mechanisms of XP, XP mouse models have been used, and mice deficient in XPA, XPC, XPD, XPG, XPF, and XPA/CSB have been produced and analysed. A recent elegant technique of targeting gene replacement in mouse embryonic stem cells has provided researche…
To understand the molecular mechanisms of XP, XP mouse models have been used, and mice deficient in XPA, XPC, XPD, XPG, XPF, and XPA/CSB have been produced and analysed. This title includes a chapter that analyzes the world distribution of XP and shows that Japan has the highest…
Repairing injured and aging tissue -- Growing body parts in the lab -- Repairing the brain -- Stem cells and cancer -- Teaching the body to fight cancer -- Stopping autoimmune disorders -- Allergies and food sensitivities - peanuts, celiac and beyond -- The future of immunothera…
"The future of medicine is happening now. Revolutionary new science is providing cures that were considered science fiction five years ago--and not with pills, surgery or radiation--but with human cells. Promising treatments now in more than 35,000 clinical trials could have dra…
"The future of medicine is happening now. Revolutionary new science is providing cures that were considered science fiction five years ago--and not with pills, surgery or radiation--but with human cells. Promising treatments now in more than 35,000 clinical trials could have dra…
"The future of medicine is happening now. Revolutionary new science is providing cures that were considered science fiction five years ago--and not with pills, surgery or radiation--but with human cells. Promising treatments now in more than 35,000 clinical trials could have dra…
"The volume outlines techniques used to study the primary mechanisms of important DNA repair pathways. The chapters in this book are organized into five sections, each discussing a specific aspect of repair biology. Part I reviews the role of post-translational modifications of …
"DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhanc…