The identification of drug targets in a given disease has been central to pharmaceutical research from the early days of pharmacology right up to the modern genomics era. Human Drug Targets provides an essential guide to one of the early most important aspects of drug discovery …
The identification of drug targets in a given disease has been central to pharmaceutical research from the early days of pharmacology right up to the modern genomics era. Human Drug Targets provides an essential guide to one of the early most important aspects of drug discovery …
This book represents an updated summary of the state of the art of the characterization of cancer stem cell/cancer initiating cell (CSC/CIC) properties. Experts provide an overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in det…
This book offers deep insights into the thermodynamics and molecular structures of the twelve catalytically active isoforms of human carbonic anhydrase (CA) with a particular focus on inhibitor binding for drug design. X-ray crystallographic structures in combination with enzyme…
This book offers deep insights into the thermodynamics and molecular structures of the twelve catalytically active isoforms of human carbonic anhydrase (CA) with a particular focus on inhibitor binding for drug design. X-ray crystallographic structures in combination with enzyme…
Intracellular and organelle targeting
"Drugs must be delivered to the target tissue or, better yet, the target organelles. A more specific target minimizes toxicity and side effects and maximizes therapeutic effect. This book is a comprehensive review of Organelle Targeting"--
Organelle and molecular targeting
Organelle and molecular targeting
"Drugs must be delivered to the target tissue or, better yet, the target organelles. A more specific target minimizes toxicity and side effects and maximizes therapeutic effect. This book is a comprehensive review of Organelle Targeting"--
Organelle and molecular targeting
Organelle and molecular targeting
"Drugs must be delivered to the target tissue or, better yet, the target organelles. A more specific target minimizes toxicity and side effects and maximizes therapeutic effect. This book is a comprehensive review of Organelle Targeting"--
Intracellular and organelle targeting
We have surpassed the omics era and are truly in the Age of Molecular Therapeutics. The fast-paced development of SARS-CoV-2 vaccines, such as the mRNA vaccines encoding the viral spike protein, demonstrated the need for and capability of molecular therapy and nanotechnology-bas…
Recent advances in this exciting field see the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance efficacy and specificity, the control and guidance of drug carriers in vasculature become …
"This book provides up to date information on the multidisciplinary field of particle engineering and drug delivery to the lungs, in relation to the advancements of nanotechnology. The text presents a unique, pragmatic focus with case studies, that help translate deep scientific…