"This volume details methods of identifying synthetic lethal, genetic interactions by various approaches in different model systems including human cancer cells. Chapters guide readers through genetic interactions in model organisms, RNA interference, CRISPR/Cas9 based genome ed…
This volume details methods of identifying synthetic lethal, genetic interactions by various approaches in different model systems including human cancer cells. Chapters guide readers through genetic interactions in model organisms, RNA interference, CRISPR/Cas9 based genome edi…
Recent developments in DNA marker technologies, in particular the emergence of Single Nucleotide Polymorphism (SNP) discovery, have rendered some of the traditional methods of genetic research outdated. Next Generation Sequencing and Whole Genome Selection in Aquaculture compreh…
Recent developments in DNA marker technologies, in particular the emergence of Single Nucleotide Polymorphism (SNP) discovery, have rendered some of the traditional methods of genetic research outdated. Next Generation Sequencing and Whole Genome Selection in Aquaculture compreh…
The year 2012 marks the tenth anniversary of the announcement of the genome sequence of the human malaria parasite Plasmodium falciparum and that of its mosquito vector Anopheles. The genome sequences were a result of the Plasmodium falciparum Genome Project. This book covers in…
In the last two decades, advances in next-generation sequencing, genome-wide genotyping arrays, and methods to obtain DNA from ancient individuals have propelled the field of population genetics such that it is now an extraordinarily powerful tool for inferring human history. Th…
Biology in genomics; Introduction to genomics; Statistics in genomics; Single-locus models; Two-locus models: the controlled crosses; Two-locus models: natural populations; Two-locus models: using linkage disequilibrium; Linkage grouping and locus ordering; Multi-locus models; l…