On the fiftieth anniversary of Watson and Crick receiving the Nobel Prize, a freshly annotated and illustrated edition of The Double Helix provides new insights into the personal relationships among James Watson, Frances Crick, Maurice Wilkins, Rosalind Franklin and a scientific…
Tracks the key experiments and discoveries that set in motion efforts to crack the genetic code, and explores the many ways humans have applied knowledge of the code to alter gene activity.
For billions of years, cells have used an ingenious system of storing and processing instructions to make proteins, the molecules that carry out vital functions for the cell. Data is warehoused in DNA molecules, copied into RNA molecules, and then read by a cell's protein synthe…
Francis Crick, who died at the age of eighty-eight in 2004, will be bracketed with Galileo, Darwin, and Einstein as one of the great scientists of all time. Between 1953 and 1966 he made and led a revolution in biology by discovering, quite literally, the secret of life: the dig…
Providing geneticists with an introduction to information theory and error-correcting codes as necessary tools of hereditary communication is the primary goal of this book. Some biological consequences of their use are also discussed, and guesses about hypothesized genomic codes…
Providing geneticists with an introduction to information theory and error-correcting codes as necessary tools of hereditary communication is the primary goal of this book. Some biological consequences of their use are also discussed, and guesses about hypothesized genomic codes…
In unstimulated cells, the transcription factor NF-κB is held in the cytoplasm in an inactive state by IκB inhibitor proteins. Activation of NF--KB is mediated by signal induced degradation of IκBα via the ubiquitin proteasome-dependent pathway. Targeting the proteins for ubiqui…
"Two Berkeley scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions."--Résumé de la notice …
Jennifer Doudna, the world-famous scientist behind CRISPR, 'one of the most monumental discoveries in biology' (New York TimesA Crack In Creation also asks us to consider what our new-found power means: how do we enjoy its unprecedented benefits while avoiding its equally unprec…
A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril.
