"Gene therapy involves altering the genes in the body's cells in an effort to treat or stop disease, instead of using drugs or surgery. This book discusses the development of gene therapy today, from the technology involved to gene correction and the advances in genome editing"--
"Gene therapy involves altering the genes in the body's cells in an effort to treat or stop disease, instead of using drugs or surgery. This book discusses the development of gene therapy today, from the technology involved to gene correction and the advances in genome editing"--
Human beings have on the order of 100,000 different genes encoding the molecules needed to build and operate the human body; defects in any one of them can lead to disastrous consequences. There are an estimated 4,000 genetic disorders, which can be every bit as devastating as t…
CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present…
1.1 Genome Engineering Technologies1.1.1 Homologous Recombination (HR) -- 1.1.2 Double-Strand Breaks (DSBs) -- 1.1.3 NHEJ Versus HDR -- 1.1.4 Zinc Finger Nuclease (ZFN) -- 1.1.5 Transcription Activator-Like Effector Nucleases (TALENs) -- 1.1.6 CRISPR/Cas9 -- 1.2 Off Target Effec…
CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present…
Animal cell biotechnology: in biologics production
This book introduces the fundamental principles and practical application of techniques used in the scalable production of proteins and virus-based gene-therapeutic products with animal cell cultures. The book reviews a broad spectrum of subjects relevant to biologics production…
