"This book tries to distinguish between the necessary and unnecessary complexity in presenting the material to a statistician or 'a data analyst'. Derivations of methods are kept simple but without losing the mathematical details." "This book also provides some necessary backgro…
Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that surrounds us today. To extract signals from high-dimensional NGS data and make…
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic tr…
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic tr…
"This book is truly unique in that it is the first comprehensive book that not only provides an introduction to the foundations of human genetics, but also includes a statistical primer, theoretical models and hands-on computer applications. There are many excellent introductory…
"This book is truly unique in that it is the first comprehensive book that not only provides an introduction to the foundations of human genetics, but also includes a statistical primer, theoretical models and hands-on computer applications. There are many excellent introductory…
This volume sets out a new statistical approach to test allelic association and genotype-specific effects in the genetic study of a disease. Primarily based on population-based association studies, the book also evaluates them compared to other methods.
