Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive tex…
An introduction to genome editing CRISPR-Cas systems -- Evolution and molecular mechanism of CRISPR/Cas9 systems -- Exploring the potential of CRISPR-Cas9 for the removal of human viruses -- Programmable removal of bacterial pathogens using CRISPR-Cas9 system -- Targeted genome …
An introduction to genome editing CRISPR-Cas systems -- Evolution and molecular mechanism of CRISPR/Cas9 systems -- Exploring the potential of CRISPR-Cas9 for the removal of human viruses -- Programmable removal of bacterial pathogens using CRISPR-Cas9 system -- Targeted genome …
Initially conceived as a strategy to remedy inherited genetic disorders, gene therapy has been successfully applied in the last decade to ameliorate the renal function compromised by progressive renal diseases and to prevent kidney allograft rejection in experimental animals. In…
Many specialists are not familiar with both drug delivery and the molecular biology of DNA vectors. Liposomes in Gene Delivery covers both-molecular biologists will gain a basic knowledge of lipids, liposomes, and other gene delivery vehicles; lipid and drug delivery scientists …
Since the first successful transplantation of umbilical cord blood in 1988, cord blood has become an important source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Significant progress has been accompanied by challenges for scientis…
by Sobol, Robert E., Scanlon, Kevin J., Nestaas, E.
fromErnst Schering Research Foundation Workshop
This book is a collection of preclinical and clinical reports on the application of gene therapy to human disease. The two methods available for delivering therapeutic genes to diseased cells, viral and non-viral vector systems, are detailed and characterized. Several reports de…
Provides detailed discussions of the most recent developments in gene mapping and manipulation to improve the diagnosis, detection, prevention, and treatment of various cardiovascular diseases--including hypertension, arrhythmias, inherited cariomyopathies, hyperlipidemia, aorti…
