Approximately 1 in 1000 children are born with congenital cardiovascular defects yearly in the US, including many abnormalities in heart valves. Tissue engineered heart valves (TEHVs) offer a solution for replacement or repair of affected valves. However, its therapeutic applica…
Recent research has demonstrated a strong correlation between the differentiation profile of mesenchymal stem cells (MSCs) and scaffold stiffness. Chitosan is being widely studied for tissue engineering applications due to its biocompatibility and biodegradability. However, its …
New 3D multi-scale modeling approaches for the structural analysis of native and prosthetic Aortic Valves (AV) are investigated. Three different nonlinear hyperelastic constitutive material models for the mechanical behavior of the AV tissue are introduced. The first is the well…
"This concise and accessible text provides an integrated overview cardiovascular medicine - considering the basic sciences which underpin the cardiovascular system and applying this knowledge to clinical practice and therapeutics. Highly visual colour illustrations complement th…
Principles of heart valve engineering
