Describes the mechanistic processes and principles underlying disease and highlights the links between disease types.
Exemplars provide the student with a deeper understanding of the mechanisms and pathophysiology of the disease process, as well as a scientific basis for understanding the medical treatment and management of a selection of key diseases.
Describes the mechanistic processes and principles underlying disease and highlights the links between disease types.
The antiviral therapeutic area continues to rapidly generate meaningful new chemical entities; for example, for HIV alone more than 25 drugs have been approved, and in the next few years many individual drugs and single tablet regimens will be approved for the treatment of hepat…
A volume that will be aimed at medicinal chemistry and emerging drug discovery scientists. The book will be organized according to the various strategies deployed for the discovery and optimization of initial lead compounds. It will be broken down into four main sections: phenot…
Lymphomas are lymphoid malignancies derived from B or T lymphocytes, and their study has been and still is paradigmatic for many aspects of cancer research. Lymphoma: Methods and Protocols presents and discusses key methods that are used in lymphoma research, partly specific for…
Over the past ten years, many powerful new techniques have been developed that have dramatically changed malaria research. The second edition of Malaria: Methods and Protocols expands upon the previous edition with current, detailed techniques for laboratory research. With new c…
This highly illustrated textbook will be an essential guide for surgeons in training. It follows a step-wise approach to performing a surgical procedure and intraoperative pictures have been incorporated. Each procedure has been written by an expert and this will be an invaluabl…
Deep brain stimulation (DBS) is increasingly used for the treatment of patients with severe Parkinson's disease and other movement disorders, but the technique and science behind it is still poorly understood by most clinicians. This book is intended to provide an overview of th…
Ovarian cancer is the most lethal malignancy of the female reproductive system and is also the fifth leading cause of cancer death in women. Sharing common characteristics of cancer, ovarian malignancy possess several clinical and biological particularities In Ovarian Cancer: Me…
The sixth edition of this international bestselling emergency medicine handbook has been completely redesigned, revised and expanded to include the very latest evidence-based guidelines for interns, SHOs and junior doctors who are new to the emergency care setting. The text foll…
The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics …
Pulmonary drug delivery has been a rapidly expanding field, moving from the traditional propellant based metered dose inhaler delivery of small asthma drugs, to a broader landscape of new devices and novel drugs for local and systemic delivery. The field has greatly expanded yet…
The ciliopathies are a group of rare diseases that often affect multiple systems within the body, and are caused by defects in the function or structure of cilia. When cilia go wrong, there are profound consequences; these are discussed in detail for the first time in Ciliopathi…
Rehearse for life in clinical practice with this easy-to-use and unique series, which combines cases drawn from real-life experiences with a refreshing approach to presentations as you would see them in day-to-day situations. Get the most from clinical practice, with Clinical Ca…