Sodium deoxycholate (DOC) was utilized to extract immunologically-active cell wall components of virulent M. bovis and M. avium, isolated from cattle in Morocco and M. fortuitum as well as related organisms e.g., N. asteroides and R. equi. The extracts from M. bovis, N. asteroid…
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Two cellular innate responses, the dsRNA protein kinase (PKR) pathway and the 2'-5' oligoadenylate synthetase (OAS)/RNase L pathway, are activated by dsRNAs produced by viruses and reduce translation of host and viral mRNAs. PKR activation results in eIF2a phosphorylation. As a …
Shigella spp. are the etiologic agents of dysentery, a severe diarrheal syndrome characterized by acute inflammation in the colon. The inflammatory response, which includes recruitment of polymorphonuclear leukocytes (PMN), damages the colonic mucosa and exacerbates the infectio…
The objectives of this project were to develop an immune assessment panel that would adequately evaluate the immune status of birds consuming mycotoxin contaminated diets, and to evaluate immune responses in chicks and turkeys, fed the Fusarium mycotoxins, fumonisin B\sb1 (FB\sb…
Nucleocapsid (N) protein was investigated as a candidate viral antigen with which to develop DNA and subunit vaccines against TCoV. Turkeys inoculated twice with the recombinant N protein developed N protein-specific lymphocyte proliferation responses and N protein-specific inte…
Building on the strengths of the first edition, the newly titled and expanded second edition remains a concise introduction to the fundamentals of immunology, with an expert synthesis of basic and clinical information., Augmented by color illustrations, and with increased emphas…
First published in 1976: The volume emphasizes studies on the role of RNA in various forms of the immune response.