Immune rebalancing: the future of immunosuppression
This book summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine. Modulation of immune responses for therapeutic purposes is a particul…
Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine. Modulation of immune respon…
Transplant immunology
A particular issue for biopharmaceuticals that has not been addressed comprehensively in any book, is the potential of an immune response to the biopharmaceutical product. That is, the human body marks the drug as a foreign body, and develops antibodies against the drug. These a…
Immunogenicity of biopharmaceuticals
by Weert, Marco van de, Møller, Eva Horn
fromBiotechnology
Immunogenicity of Biopharmaceuticals is the first book to comprehensively address the potential of an immune response to biopharmaceuticals. It is intended to give a broad overview of the current state-of-the-art regarding this subject. The chapters range from an overview of the…
A particular issue for biopharmaceuticals that has not been addressed comprehensively in any book, is the potential of an immune response to the biopharmaceutical product. That is, the human body marks the drug as a foreign body, and develops antibodies against the drug. These a…
In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture "Immunological Recognition of Self" emphasizing the central argument of immunological tolerance in "How does the vertebrate organism recognize self from nonself i…
Natural Killer T cells
by Terabe, Masaki, Berzofsky, Jay A.
fromCancer Drug Discovery and Development
This book will cover primary roles of NKT cells in immunity to cancer, in both mouse tumor models and cancer patients. There are several chapters describing general aspects of NKT cells.
Natural killer T (NKT) cells are CD1d-restricted T cells that respond to lipid, not protein, antigens presented by CD1d, which is a non-classical MHC class I-like molecule.¡ This relatively small but pivotal T cell population bridges the gap between innate and adaptive immunity …
As the principal antigen-presenting cells to T cells, dendritic cells (DCs) have a key role in the balance of immunity and autoimmunity. They are essential in two major, converse roles - eliciting T cell immune responses to pathogenic material, and maintaining peripheral toleran…
IMMUNOREGULATORY ROLE OF THYMUS
by Dabrowski, Marek P., Dabrowska-Bernstein, Barbara K.
fromCRC revivals
First published in 1990. This important new text covers a wide area of thymology in both the theoretical and practical aspects. In view of current information, a crucial role of endocrine thymus is presented in the creation, maintenance, and senescence of neuro-endocrine-immune …