A continuous multi-locus model describing the evolution of a large population of a diploid organism is studied. It is assumed that only the forces of natural selection and recombination are operating. The use of a non-Euclidean metric greatly clarifies the dynamical properties o…
Using an interdisciplinary approach, the authors provide an adaptionist interpretation of the basic features of recombination, its evolutionary significance as a key process in reproduction and its importance in genetic mapping. The book synthesizes much recent information in th…
This handbook on the statistical issues of genomics covers current methods and the tried-and-true classical approaches, providing a complete picture of genome statistics. It contains much basic information on the use of statistics in genomics, including how to determine a sample…