Lymphomas frequently retain wild-type (wt) p53 function but overexpress HDM2, compromising p53 activity. Therefore, lymphoma is a suitable model for studying therapeutic value of disrupting HDM2-p53 association by small-molecule inhibitors (SMIs). HDM2 SMIs have been developed a…
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Previous studies of the pattern of lymphoma in multi-ethnic West Malaysian population have shown a high frequency of EBV association in childhood Hodgkin's lymphoma (HL) and adult NK/T-cell lymphomas, with a predilection of the former in Indians and the latter in Chinese. This t…
"Many things have changed since 2014, when I completed the previous edition of this book. The World Health Organization (WHO) published in 2017 an update of the Classification of Tumours of Haematopoietic and Lymphoid Tissues, and in 2019 the European Organization for Research a…
"Many things have changed since 2014, when I completed the previous edition of this book. The World Health Organization (WHO) published in 2017 an update of the Classification of Tumours of Haematopoietic and Lymphoid Tissues, and in 2019 the European Organization for Research a…
"Many things have changed since 2014, when I completed the previous edition of this book. The World Health Organization (WHO) published in 2017 an update of the Classification of Tumours of Haematopoietic and Lymphoid Tissues, and in 2019 the European Organization for Research a…