Retrometabolic drug design and targeting
by ebrary, Inc, Bodor, Nicholas, Buchwald, Peter
This volume provides information related to the difficulties in treating cancers through targeted drug delivery. It examines our current understanding of cancer biology as well as potential technologies that may achieve enhanced drug delivery to tumors.
From its introduction, oncological chemotherapy has been encumbered by its poor selectivity because most antiproliferative drugs are toxic not only to tumor cells but also to important populations of the body's non-neoplastic cells. The resultant problems with unwanted side effe…
Opening with a general introduction on chemokine function and chemokine receptor biology, the handbook goes on to cover the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including HIV/AIDS. The second ha…
Opening with a general introduction on chemokine function and chemokine receptor biology, the handbook goes on to cover the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including HIV/AIDS. The second ha…
Drug delivery: fundamentals and applications