The constant internal change in the field of cell-penetrating peptides (CPPs) is due to recent research uncovering apparent ambiguities in cellular uptake. There is still neither a common terminology nor a uniform explanation for the penetrative mechanism of cell-penetrating pep…
Biomembrane electrochemistry
by Blank, Martin, Vodyanoy, Igor
fromAdvances in chemistry series
The fundamental membrane processes of living cells are electrical in nature. Each process involves charge movement in a specialized protein structure, where part of the protein forms a channel for the conduction of ions. A 5-year program initiated by the Office of Naval Research…
The recent dramatic expansion of our knowledge about how cell surface receptors transmit signals to the nucleus, together with the identification of key signaling and cell-cycle-regulating molecules, has provided a major opportunity to search for novel targets for therapeutic in…