Current trends in the fight against malaria suggest that further progress will be difficult with the use of insecticide-based control measures alone. Without major reductions in the burden of malaria registered in the past few years, the use of additional interventions with syne…
Arboviral diseases account for more than 17% of all infectious diseases globally, among the most prevalent are dengue fever and chikungunya, with over half of world’s population at risk of infection. Although mortality is generally low, the morbidity caused by these pathogens is…
The Aedes aegypti mosquito is the principal vector of the viruses that cause dengue, Zika, chikungunya, and yellow fever. There have been recent outbreaks of all these diseases, and the number of dengue cases has increased 30-fold in the past 50 years. Of the diseases Ae. aegypt…
Mosquitoes (Diptera: Culicidae) are globally important pests that have strong population responses to environmental change. They are also model organisms for testing theories about the ways that species interactions structure ecological communities, and the mechanisms by which d…
Mosquitoes which belong to the genera Aedes, Anopheles and Culex are considered to be medically important due to the number of diseases they transmit. This study focuses on various aspects of mosquito biology including parallel immune pathways, use of CRISPR-Cas as RNA interfere…
Insecticide application via indoor residual spraying (IRS) and long-lasting insecticide-treated bednets (LLIN) has been a key component in combating malaria in sub-Saharan Africa, with pyrethroids being the traditionally recommended insecticides. However, the resistance of Anoph…
Malaria is a serious and life-threatening mosquito-borne disease that every year affects over 200 million individuals and causes 400,00 deaths. An additional 0.5 billion people globally are at risk of malaria infection. The unique role of climate in influencing malaria transmiss…
Disease transmission is a product of mechanisms and interactions at multiple levels of biological organization, and a comprehensive understanding of these processes is essential to disease control. Malaria parasites, for example, can infect dozens of vector species and undergo c…
Malaria caused by the replication of Plasmodium falciparum parasites within human red blood cells (RBCs) remains a leading cause of human death by infectious disease. Over several thousand years, high childhood mortality from malaria has produced strong selection for human resis…
Malaria is a mosquito-borne parasitic disease that poses a significant public health threat to millions of people worldwide. Malaria is transmitted by female Anopheles mosquitoes. Mosquitoes in the genus Anopheles are incredibly diverse, with different ecologies and behaviors th…
Introduction WHO malaria elimination targets require sustained and robust surveillance systems to identify difficult-to-diagnose, low-density malaria infections which threaten control efforts. The WHO 'T3: Test, Treat and Track' initiative further reinforces the importance of th…