Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the need to deliver a therapeutic vector to all muscles throughout the body. In Muscle Gene Thera…
Skeletal muscle is a highly plastic tissue that constitutes approximately thirty percent of total body mass and adapts rapidly to changing functional demands. Skeletal muscle is not only the generator of force production, but also plays a crucial role in whole body metabolism an…
by Dubowitz, Victor, Sewry, Caroline A., Oldfors, Anders
by Dubowitz, Victor, Sewry, Caroline A., Oldfors, Anders
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Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, an internationally renowned figure …
"Muscle disease represents an important health threat to the general population. Unlike diseases affecting other tissues/organs, therapeutic options are quite limited for many inherited muscle diseases such as Duchenne muscular dystrophy. There is essentially no cure. Gene thera…
"Availability and standards on techniques to estimate muscle mass (or lean body mass) in epidemiological studies were becoming available. Based on these parameters, sarcopenia was operationally defined as a gradual loss of muscle mass. For instance, Baumgartner used a definition…
"Availability and standards on techniques to estimate muscle mass (or lean body mass) in epidemiological studies were becoming available. Based on these parameters, sarcopenia was operationally defined as a gradual loss of muscle mass. For instance, Baumgartner used a definition…
The legacy of Geoff Maitland and his seminal work, Peripheral Manipulation, continues in this fifth edition, with Elly Hengeveld and Kevin Banks leading an international team of experts who demonstrate how to manage peripheral neuromusculoskeletal disorders using the principles …
Orofacial pain - defined as pain lasting over three months in the mouth or face - is increasing in prevelance, with approximately 7% of the UK population having experienced it. It is currently managed by either dentists or general medical practitioners, both of whom have radical…
This book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters navigate the nuances of these …
