The evaluation of potential mutagenic activity is a critical step in the assessment of the safety of both new and pre-existing chemical types. In Genetic Toxicology: Principles and Methods, expert contributors help to satisfy the demand for education in this tremendously importa…
Rasnick, who worked in the pharmaceutical/biotech industry to develop protease inhibitors and founded three biotech companies, explains the chromosomal imbalance (aneuploidy) theory of cancer, as opposed to the gene mutation theory. He describes how gene mutations are not powerf…
This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols. Since the first edition, major advances and discoveries have made chromosomal mu…
The issue of male germ line mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile over recent years. Mutations are thought to be becoming more prevalent as a result of: exposure to chemicals in the environment, anti canc…
The issue of male germ line mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile over recent years. Mutations are thought to be becoming more prevalent as a result of: exposure to chemicals in the environment, anti canc…
Male-mediated developmental toxicity
by ebrary, Inc, Anderson, Diana, Brinkworth, Martin H.