Electronic health records (EHRs) are growing at an exponential rate, and predictive analysis of this data can help physicians determine a patient’s condition at an early stage. In order to perform predictive analytics, various factors need to be considered, including demographic…
A salient difference between artificial and biological neural networks is the complexity and diversity of individual units in the latter (Tasic et al., 2018). This remarkable diversity is present in the cellular and synaptic dynamics. In this study we focus on the role in learni…
Neuromorphic computing is a computing field that takes inspiration from the biological and physical characteristics of the neocortex system to motivate a new paradigm of highly parallel and distributed computing to take on the demands of the ever-increasing scale and computation…
Transitions between neuronal states are essential to cognitive and motor processes but are less understood than the states themselves. Transitions often consist of irregular activity which computational models predict is chaotic, and thus activity is deterministic and sensitive …
Calcium Measurement Methods
by Verkhratsky, Alexei, Verkhratskii, A. N, Petersen, O. H, Verkhratskiæi, A. N.
fromNeuromethods
Since the introduction of fluorescent calcium indicators and the subsequent development of capacities for real-time monitoring and imaging of calcium movements in the intact cells studied in isolation, in situ and in vivo, the complex and vital calcium signalling system has been…
Since the introduction of fluorescent calcium indicators and the subsequent development of capacities for real-time monitoring and imaging of calcium movements in the intact cells studied in isolation, in situ and in vivo, the complex and vital calcium signalling system has been…
Cell-free circulating DNA (cfDNA) released from dying cells is emerging as an important tool for the diagnosis of disease. However, the utility of cfDNA is limited in conditions in which involved tissues have a normal genome or unknown mutations. I have developed an approach to …
Vertebrates possess lineage-specific characteristics. These include paired anterior sense organs and a robust, modular head skeleton built of cellular cartilage and bone. All of these structures are derived, at least partly, from an embryonic tissue unique vertebrates - the neur…
Vertebrates possess lineage-specific characteristics. These include paired anterior sense organs and a robust, modular head skeleton built of cellular cartilage and bone. All of these structures are derived, at least partly, from an embryonic tissue unique vertebrates - the neur…
Voltage-dependent anion channels (VDAC) in the plasma membrane induce apoptosis
by Akanda, Nesar, Elinder, Fredrik, Jalonen, Tuula, Linköpings universitet, Institutionen för klinisk och experimentell medicin, Linköpings universitet, Hälsouniversitetet
fromLinköping University Medical Dissertations
Apoptosis, or programmed cell death, is essential for proper development and functioning of the body systems. During development, apoptosis plays a central role to sculpt the embryo, and in adults, to maintain tissue homeostasis by eliminating redundant, damaged or effete cells.…