How do we forget? Why do we need to forget? This book intends to answer to these and other questions. It aims to demonstrate that each one is who it is due to their own memories. Thus, distinguish between the information we should keep from those we should forget is an difficult…
This volume presents cutting-edge techniques to design, fabricate and use compartmentalized microfluidic devices. Chapters encompass axon guidance and manipulation, compartmentalized devices for synapse manipulation, cell populations interaction either in physiological or pathol…
This volume describes the methods of both in vivo and in vitro electroporation using ferrets, rats, mice, chickens, and zebrafish. Recent advances of experiments using the tetracycline-regulated gene expression and Tol2 transposon systems are also included. Written in the popula…
This vibrant collection delivers a laboratory roadmap of testing cognition in the rodent. While rodents and mazes are the main center and focus of this book, many aspects in the field of learning and memory are discussed and detailed, spanning from the molecular to the human, wi…
The metabolomics and systems biology approach to research can be applied to many disciplines. This book provides a solid introduction to medical metabolomics and systems biology, and demonstrates how they have been applied to studies in medicine and human health, including nutri…
Since information in the brain is processed by the exchange of spikes among neurons, a study of such group dynamics is extremely important in understanding hippocampus dependent memory. These spike patterns and local field potentials (LFPs) have been analyzed by various statisti…
This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging…
As autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease. Split into five sections, "Organism Models o…
Muscarinic receptor: from structure to animal models
by Jakubik, Jan, Myslivecek, Jaromir
fromNeuromethods
This volume provides methods for characterization of muscarinic receptor in crystallography studies that advanced our understanding of structural properties and activation mechanism of muscarinic receptors and are cornerstone in molecular modeling and computer-based approaches t…
"Alzheimer's disease (AD) and many other neurodegenerative disorders are multifactorial in nature, involving a combination of genomic, epigenomic, network dynamic and environmental factors. A proper investigation requires new integrative Systems Biology approaches, at both the e…
This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroim…
Neuronal noise
by Destexhe, Alain, Rudolph, Michelle
fromSpringer series in computational neuroscience
This volume of Progress in Brain Research provides a synthetic source of information about state-of-the-art research that has important implications for the evolution of the brain and cognition in primates, including humans. This topic requires input from a variety of fields tha…