Osteoporosis, a skeletal disorder characterized by compromised bone-strength and an increased risk of bone fracture, is becoming increasingly prevalent, and the health and economic burden of osteoporosis is only expected to increase as the population ages. Osteoporosis dispropor…
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Background: Osteoporosis and vertebral fractures are common in patients with Duchenne Muscular Dystrophy (DMD) treated with glucocorticoids. Bisphosphonates (BP) have been used in pediatric patients for treatment of osteoporosis. However, the long-term effects of oral BP therapy…
Bone makes up a framework that provides protection for internal body organs. The homeostasis of bone is maintained by a balanced process involving old bone degradation and new bone formation. However, this balance can be altered in pathophysiological conditions such as in postme…
Bone is a complex fibrous biological nanocomposite material optimized to avoid catastrophic failure and to perform a variety of mechanical functions, most notably load bearing. The fracture behaviour of bone is expected to be controlled by the various structural features present…
Osteoporosis has affected millions of patients worldwide and is a continuing concern for the increasing ageing population. It is a skeletal disease due to abnormal bone growth and resorption, characterized by low bone mass. Onset could be due to genetics and family history or ac…
The objective of this study was to examine effects of ultrasound on a disuse bone model and osteoblast cell cultures in simulated microgravity. This will help us understand the effects of ultrasound on microgravity induced osteoporosis and provide a non-invasive and more targete…