This book is the proceedings of the highly successful 5th International Conference on Progress in Alzheimer's Disease and Parkinson's Disease which took place from March 31st to April 5th, 2001, in Kyoto, Japan. This international conference was organized as a joint Congress wit…
An account of the treatment of patients who had used tainted synthetic heroin and, as a result, were unable to speak or move. Relates how attempting to treat them led to research in the use of fetal tissue transplants in the treatment of Parkinson's Disease and other degenerativ…
What makes us move? Human movement disorders like Parkinson’s disease have long suggested a vital role for dopamine in movement initiation, but there exists surprisingly little evidence connecting endogenous dopaminergic activity to a causal role in this process. Although “stand…
Background:Parkinson’s disease (PD) is a neurodegenerative disease characterized by rigidity, hypokinesia, tremor and postural instability. PD is a clinical diagnosis based on neurological examination, patient history and treatment response. Similar symptoms can be caused by oth…
Background and aims: The occurrence of RBD in the context of psychiatric disorders (psy-RBD) has been regarded simply as a drug-induced condition. However, recent studies suggested that psy-RBD was associated with clinical and imaging biomarkers related to neurodegeneration. The…
This study examined the effects of laryngeal activity on articulation by comparing the articulatory kinematics of the /i/ and /u/ vowels produced in different speaking conditions (loud, comfortable, soft and whisper). Participants included 10 males and 10 females with no history…
Neurological disorders are chronic diseases that may negatively affect one’s physical, cognitive, and psychosocial functioning. They also commonly affect patient’s quality of life. The complexity of these disorders and associated outcomes create unique challenges in one’s abilit…
La dyskinésie induite á la L-Dopa se manifeste sous forme des mouvements anormaux et involontaires survenant suite á l'administration pulsatile et à long terme de L-Dopa chez les patients parkinsoniens. Il s'agit d'une complication fréquente, invalidante, dont le traitement médi…
Non-motor symptoms (NMS) are common in Parkinson's disease (PD) and are considered the most disturbing symptoms to both patients and caregivers. Sleep disorders including rapid-eye-movement sleep behavior disorder (RBD), obstructive sleep apnea (OSA), restless legs syndrome (RLS…
La maladie de Parkinson est une effroyable pathologie affectant plus de 130 000 canadiens. C'est la deuxième maladie neurodégénérative, après la maladie d'Alzheimer. Des études récentes montrent que de plus en plus d'indices semblent converger vers le stress oxydant comme un des…
Parkinson disease (PD) is an incurable movement disorder clinically characterized by resting tremor, bradykinesia and other cardinal features. A Japanese kindred with autosomal dominant PD showed linkage to a novel locus on chromosome 12pl 1.2-ql3.1, subsequently given the desig…
