polarity

The ESCRT machinery has a well established role within the endocytic pathway. Studies conducted in Drosophila have identified ESCRT proteins as important regulators of epithelial cell polarity and growth. Consequently ESCRTs have been classified as potential tumour suppressors. …

A key part of a fruit fly's development is the formation of segmentsin its body. These structures are built by the protein forms of so-called segment polarity (SP) genes. It is the asymmetric expression of SP genes which creates the fruit-fly's segmental structure. The SP genes …

This thesis describes stereospecific fluorination reactions, and addresses the synthesis of fluorosugars. In Chapter 1, the influence of fluorine on the physical properties of organic molecules, as well as its stereoelectronic effects, are introduced. Furthermore, an overview of…

High quality and accurate computational data was obtained through first principle quantum mechanical calculations originated from density functional theory without the inclusion of empirical data (ab initio). The support of the computing facility NGS allows us to carry out our r…

The term impostor phenomenon emerged in the late 1970s during the second wave of the feminist movement in the United States, and interest in the phenomenon has continued over the past four decades, with research examining the causes and effects of individuals’ self-doubt and imp…

Studies of polarity-sensitive items (PSIs) such as English any have long focused on characterizing the contexts in which PSIs appear ('the licensing problem'). Recently, the focus has shifted to examining the lexical content of PSIs and deriving their limited distribution from t…