Prognosis

Prognostic factors come in a variety of forms and may be patient, tumour or environmental related. This thesis examines the interaction of prognostic factors for a variety of tumour types. It particularly focuses on single nucleotide polymorphisms (SNPs) of the vascular endothel…

Background: Peri-implant diseases, peri-implantitis (PI) and peri-implant mucositis (PIM), are highly prevalent in subjects with dental implants. Despite this prevalence, diagnosing peri-implant disease (PID) remains challenging because of lack of accuracy and precision of perio…

Objective: To retrospectively analyze local and systemic factors that resulted in the short-term tooth loss that were previously assigned a favorable prognosis in patients who were seen and treated at the University of California San Francisco (UCSF) School of Dentistry over an …

Background: Prostate Cancer (PCa) is the second most common malignancy among men in the world. In Sweden about 10,000 new cases are diagnosed each year. Mortality rates have been rather stable but have declined the past decades due to early diagnosis and treatment at the expense…

Purpose: Uncertainty is unavoidable and can be distressing to patients, yet little is known about (a) the frequency and domains of uncertainty expressed by patients with advanced cancer when communicating with a palliative care team or (b) whether that uncertainty changes over t…

Chronic hepatitis C (CHC) is a leading cause of hepatic fibrosis and cirrhosis. Fortunately, treatment has been revolutionized by the recently introduced direct-acting antivirals (DAAs). However, prompt access to DAA therapy remains a challenge owing to exorbitant drug costs, as…