Protein-protein interactions (PPIs) are strongly predictive of functional relationships among proteins in virtually all processes that take place in the living cell. Therefore, the comprehensive exploration of interactome networks is one of the major goals in systems biology. Th…
This book provides a comprehensive overview of the fundamental aspects of protein-protein interactions (PPI), including a detailed account of the energetics and thermodynamics involved in these interactions. It also discusses a number of computational and experimental approaches…
Cell migration is an extremely complex but also a carefully orchestrated process. It involves the constant reconstruction of the cell shape, in order to adapt to an ever-changing plethora of external and internal stimuli. Time lapse movies of migrating cells often demonstrate a …
Michael D. WendtProtein-Protein Interactions as Drug TargetsShaomeng Wang, Yujun Zhao, Denzil Bernard, Angelo Aguilar, Sanjeev KumarTargeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics Kurt Deshayes, Jeremy Murray, Domagoj VucicThe Development of Small-…
Michael D. Wendt Protein-Protein Interactions as Drug Targets Shaomeng Wang, Yujun Zhao, Denzil Bernard, Angelo Aguilar, Sanjeev Kumar Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics Kurt Deshayes, Jeremy Murray, Domagoj Vucic The Development of Sm…
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers computational prediction RNA structure and dynamics, including such topics as computational modeling of RNA secondary a…
