Proteases decisively contribute to cancer development and promotion by regulating the activities of growth factors/cytokines and signaling receptors, as well as the composition of the extracellular matrix, thereby suppressing cell death pathways and activating cell survival path…
(Publisher-supplied data) In recent years, serine proteases and matrix metalloproteinases (MMPs) have gained considerable attention in tumor biology. For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling. This book provides a compreh…
This volume offers an update on this aspect of cancer treatment, its interest bias and possible clinical implications, providing an evaluation of the mechanisms of action of proteases and their inhibitors in tumour biology.
