This volume explores the considerable efforts that have been directed towards the development of G Protein-Coupled Receptors (GPCR) screening assays in order to disclose GPCR acting compounds, elucidate signaling mechanisms or evaluate compound's efficacy. New discoveries in the…
2.1. The G Protein Complex2.2. Introduction to RGS Proteins; 3. RGS Proteins in Osteoblasts; 3.1. RGS2 in Osteoblasts; 3.2. RGS5 in Osteoblasts; 3.3. Axin in Osteoblasts; 4. RGS Proteins in Osteoclasts; 4.1. RGS10 in Osteoclasts; 4.2. RGS12 in Osteoclasts; 4.3. RGS18 in Osteocla…
RGS Protein Physiology and Pathophysiology describes the current, state-of-the-art research occurring in the laboratories of leaders in the RGS protein field that utilize genetic mouse models to interrogate the function of RGS proteins in vivo. Each chapter describes the elucida…
This fully updated edition targets not only those assays directly involved in the discovery of GPCR-active compounds but also those involved in cell-based experiments designed to study physiological responses. Whether coming from academia or industry, or being an experienced res…
Incorporating a bench-top format, G Proteins: Techniques of Analysis covers essential methods - with a commitment to those techniques of proven and current utility. It offers an in-depth description of protocols, together with theory and representative data. It includes expressi…
G Proteins: Techniques of Analysis covers essential methods - with a commitment to those techniques of proven and current utility. G Proteins: Techniques of Analysis includes expression and functions analysis of G proteins; evaluation of covalent modifications and other regulato…