Marine polysaccharides have been widely used as a source of nutritional supplement for various therapeutic applications. Uncertainties and significant gaps in our knowledge about the macromolecular properties of these substances have limited their use particularly in the pharmac…
"6" Result
Sort By:
The complicated task of interpreting the many ubiquitin signals is mediated by specific ubiquitin binding domains. The investigations discussed in this thesis focus on two very different ubiquitin binding domains. Chapters 3 to 5 detail the structural characterisation of the ubi…
A good QSAR model comprises several components. Predictive accuracy is paramount, but it is not the only important aspect. In addition, one should apply robust and appropriate statistical tests to the models to assess their significance or the significance of any apparent improv…
This thesis concerns two areas of bioinformatics related by their role in protein structure and function: protein structure prediction and post translational modification of proteins. The dihedral angles Ψ and Φ are predicted using support vector regression. For the prediction o…
Thesis describes synthetic studies directed towards evaluating the biosynthetic relationships between several novel polycyclic diterpenes, including bielschowskysin 1, verrillin 2, plumarellide 3 and intricarene 4, and their probable furanobutenolide -based cembrane precursors, …