Radiation in medicine and biology
Dr. Khan's classic textbook on radiation oncology physics is now in its thoroughly revised and updated Fourth Edition. It provides a thorough understanding of the physics and practical clinical applications of advanced radiation therapy technologies, including 3D-CRT, stereotact…
A utilização de radionuclídeos que emitem partículas alfa ocorre desde a sua aprovação clínica em 2013, com diferentes graus de sucesso. Apesar da sua utilidade clínica, pouco se sabe sobre o mecanismo de ação das partículas alfa em condições clínicas e estudos precisos da sua d…
A doença oncológica é considerada um problema de saúde pública a nível mundial devido á sua crescente morbilidade e mortalidade no século XXI. Esta doença apresenta, igualmente, um grande impacto social devido aos custos económicos ligados à prevenção, tratamento e reabilitação …
Despite advancements in our ability to diagnosis and treat cancer, cancer progression still occurs in many patients. Disease progression at sites other than the treated tumor remains an obstacle for improved patient outcomes. In-situ cancer vaccine strategies use immunotherapeut…
Cancer is one of the deadliest diseases in human history with extremely poor prognosis. Although many traditional therapeutic modalities—such as surgery, chemotherapy, and radiation therapy—have proved to be successful in inhibiting the growth of tumor cells, their side effects …
In this thesis 6 and 18 MV photon beams for a Varian linear accelerator were simulated using a general purpose Monte Carlo code MCNP5 (Monte Carlo N-Particle Transport Code). The potential of MCNP5 is explored to calculate the dose in high dose gradient regions. In addition, MCN…