"Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II - reducing chromosome number from the diploid level to a haploid genome, reshuffling the homologous chromosomes by their centromeres, and recombining chromosome arms by crossing-over. In animals, in…
Using an interdisciplinary approach, the authors provide an adaptionist interpretation of the basic features of recombination, its evolutionary significance as a key process in reproduction and its importance in genetic mapping. The book synthesizes much recent information in th…
DNA recombination and repair
by Smith, Paul J., Jones, Christopher J.
fromFrontiers in molecular biology
DNA recombination and repair
DNA recombination and repair
by Jones, Christopher John, Smith, Paul J.
fromFrontiers in molecular biology
The processes of DNA recombination and repair are vital to cell integrity -- an error can lead to a disease such as cancer. These processes are therefore expanding areas of research and are now being taught in many undergraduate and postgraduate courses. Filling a need for timel…
Genome Stability: DNA Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of chromosomal breaks. The text presents a definitive history of the evolution of molecular models of DNA repair, emphasizing current…