Sjogren's syndrome

Primary Sjögren’s syndrome is a systemic autoimmune disease primarily affecting salivary and lacrimal glands, but patients may also have other organ involvement. Development of Sjögren’s syndrome has been associated with genetic polymorphisms and aberrances in innate and adaptiv…

The ubiquitous ɣ-herpesvirus Epstein-Barr virus (EBV) infects B cells and modifies their differentiation programme leading to B cell activation and immortalization. Although different evidences support a link between EBV infection and rheumatoid arthritis (RA) and Sjogren’s synd…

Primary Sjögren's syndrome (pSS) is a chronic disabling disorder affecting a substantial proportion of the general population. Clinical manifestations are heterogeneous and can be severe or life-threatening. Currently, no specific tests are available for diagnosis of pSS. Therap…