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This book draws together contributions from authorities in the field and fills the urgent need to communicate the state of the art to a general statistical audience. Emphasis is placed on practice rather than theory, although fundamental theoretical concepts are discussed. The i…
Genome assembly is the process of merging fragments of DNA sequences produced by shotgun sequencing in order to reconstruct the original genome. It is complicated by repeated regions in genomes, sequencing errors, and experimental biases. Here we focus on our efforts to confront…