[Publisher-supplied data] Since the initial discovery of the claudins, the field of tight junctions and cell polarity has become increasingly energized, mainly due to the fact that the claudins have provided an opportunity to understand the molecular basis of the tight junction …
"As the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field. Since its publication in 1992, there has been an explosion of information about tight junctions,…
Inflammatory bowel disease (IBD), which includes the subtypes Crohn's disease (CD) and ulcerative colitis (UC), is a common disease particularly in the Western world. IBD is characterised by inflammation of the small intestine and/or colon. The two subtypes affect different gut …
The main objective of my PhD research has been to explore the mechanisms involved in the transport across the blood-brain barrier (BBB) of two very interesting molecules, Prions and GABA that have been poorly studied in the context of the BBB. GABA transport at the BBB and devel…