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Notch Signaling: Methods and Protocols focuses on molecular, biochemical, and bioinformatics aspects of Notch signaling. Chapters analyze the Notch interactome, post-translational modifications of Notch, ligand binding assays, methods to assess proteolytic cleavage, and transcri…
Hyaluronan signaling and turnover
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Type: Book
La 4e de couverture indique : "The second edition of this volume provides novel protocols for the study of newly discovered function and modifications of components of the Hh pathways. The first few chapters discuss methods for stable delivery of soluble Hh proteins in cell cult…
This detailed volume assembles comprehensive protocols to assist with the study of structural, molecular, cell biological, and in vivo facets of GPCRs, and to enable the development of experimental tools for screening novel GPCR drugs. Sections explore the tweaking of ligands, b…
![TGF-[beta] signaling](https://covers.openlibrary.org/b/isbn/9781493929658-M.jpg?default=false)
Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention * In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and a…
This detailed book explores the technical breakthroughs with biophysical and cell biological approaches that have advanced the study of molecular mechanisms underlying the generation and transduction of the hedgehog (HH) signal, indicating the important role of sterols in this p…
This volume, along with its companion (volume 475), presents methods and protocols dealing with thiol oxidation-reduction reactions and their implications as they relate to cell signaling. The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one…
Today, we are surrounded by a multitude of different chemicals that are essential components of our everyday life. As a consequence, there are various hazardous substances like dioxins, phthalates and flame-retardants circulating in the environment. These have an impact on ecosy…