Transposons

Short Interspersed Nuclear Elements (SINEs) are non-autonomous mobile elements present in eukaryotic genomes. SINEs are mobilized in the form of a transcribed RNA intermediate in a `copy and paste’ process referred to as retrotransposition, by making use of the enzymes encoded b…

Transcription factors (TFs) confer specificity to transcriptional regulation by binding specific DNA sequences and ultimately affecting the ability of RNA polymerase to transcribe a locus. The C2H2 zinc finger proteins (C2H2 ZFPs) are a TF class with the unique ability to divers…