Preeclampsia and fetal growth restriction (FGR) are common and costly obstetric complications. Both conditions are associated with immediate and remote mortality and morbidity for the mother and the offspring. Impaired placentation and aberrant maternal systemic responses are im…
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The ovarian follicle is an individual functional unit that provides the optimal environment for the oocyte within to develop. This thesis outlines the research in the field of ovarian follicular dynamics that has already been established, and further develops these findings to e…
Increasing the uptake of elective single embryo transfer is necessary to achieve the 10% HFEA limit for multiple IVF births in 2011. This thesis aims to explore patients’ and clinicians’ attitudes to eSET and to promote effective decision making regarding embryo transfer. Study …
Chorionic plate (CPA) and stem villous (SVA) arteries located at the fetal and maternal interface of the placenta respond to stimuli including hypoxia and acidic pH which can be the result of an intermittent blood supply. Unlike other vascular tissue the placenta lacks nervous c…
This retrospective cohort study, examined pregnancy and birth related outcomes for 32,895 births between 1st January 1992 and 31st December 2001 in two maternity units in the East Midlands. The study compared seven outcomes in younger teenagers (<16 year), older teenagers (17-19…
A number of women continue to smoke in pregnancy despite the associated risks to their health and that of their unborn child. Little is known about their attitudes towards the smoking cessation support which is available to them and this thesis used a Theory of Planned Behaviour…
This study explores the nature of competence required to fulfil the role of the midwife, learning to become competent, and professional learning beyond registration. The research was undertaken through a qualitative, case study approach, exploring competence as a phenomenon, as …