Thesiss

The rate of accumulation of nucleic acid sequence data produced by next generation sequencing technology has in some ways outpaced the development of theory and methods for analyzing such data. In this dissertation, I explore the advantages of, and how to best implement, whole g…

Alternative splicing (AS) is a common post-transcriptional process in eukaryotic organisms, by which multiple distinct functional transcripts are produced from a single gene. Because of its potential role in expanding transcript diversity, interest in alternative splicing has be…