Thesiss

Due to the unique religious and cultural characteristics of Saudi Arabia, evaluating knoweldge and exploring attitudes toward cancer genetic tests (CGT) are important for bolstering currently underdeveloped CGT services. This cross sectional study was carried out in the form of …

KRAS (Kirsten rat sarcoma) oncoprotein is mutationally activated in ~40% of colorectal cancers (CRC) and KRAS mutation state is an excellent predictor of the failure of a cancer to respond to conventional chemotherapy or targeted therapy. The colonic epithelium provides a biolog…

Approximately 5–10% of cancers are thought to be hereditary, caused by pathogenic variants in genes associated with inherited cancer syndromes. Previvors, individuals who have a higher predisposition to cancer due to genetic or other risk factors, have specific healthcare and ps…