Mathematical modeling based on rigorous integrated description of any process is a fast, efficient and economical way of gaining insight into the complex process, especially biochemical processes. This dissertation which is divided into four parts presents the mathematical model…
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In spite of the importance of filamentous actinomycetes, the number of published reports for engineering aspects of fermentation (e.g. effect of agitation) are rare compared with filamentous fungi. Intensive mechanical agitation is necessary for adequate oxygen transfer rate and…
Among the various fungal strains screened for citric acid production, Aspergillus niger is known to produce considerable amounts of citric acid and other organic acids when cultivated in carbohydrate-rich medium in solid substrate fermentation (SSF). Since A. niger on a solid su…
There is an increasing consumer demand for dairy products which are safe and free from additives. Microbial starter strains, in combination with other factors, were studied for their contribution to the control of unwanted microbes, and maintaining the quality of soft cheese. Th…
Antimicrobial resistance poses a major problem to health and new alternatives to antibiotics are required. Bacteriophages are viruses able to selectively kill bacteria and they can be exploited to treat infections. Another alternative to antibiotics that can be used to treat bac…
Filamentous fungi are used in the production of both homologous and heterologous proteins due to their desirable growth characteristics. However, the product concentrations of heterologous proteins are usually much lower than those of homologous proteins. Apart from the difficul…