Thesiss

Previous work in our group has been directed towards the synthesis of crown-ethers for use in the selective complexation of metal ions and as chiral ligands for use in asymmetric catalysis. The development of a modular approach to macrocycle assembly has enabled the synthesis of…

The carbonylation of methanol to acetic acid is one of the most important applications in homogeneous catalysis. The first chapter comprises a review on the mechanistic studies into the catalytic cycle of the ‘Monsanto process’ and includes some of the most prominent studies int…

This thesis contains three parts: 1) The briefly review of chiral P, N-ligands. 2) The summary of triazole as ligands. 3) The attempt of designing, synthesizing the chiral triazole ligands.

The synthesis of sterically hindered β-diketones via Claisen-type condensations using potent electrophiles is described. Specifically, examples bearing ortho-biphenyl and meta-terphenyl groups have been optimized and are prepared in high yields. A theoretical rationale for the m…