Thesiss

Chromosomal type II toxin-antitoxin (TA) modules consist of a pair of genes that encode two components: a stable toxin and a labile antitoxin interfering with the lethal action of the toxin through protein complex formation. Typically, the toxin inhibits an essential cell functi…

Streptococcus mutans, an oral pathogen, is considered as a principle etiological agent of dental caries. To colonize successfully in the oral cavity, this organism encounters fierce competition with other oral microbiota and this process is facilitated by ribosomally synthesized…

Brief Background: Streptococcus mutans (S.mutans) is the pioneering pathogenic bacteria responsible for the initiation of dental caries. Controlling S.mutans activity using dental probiotics may have an impact on caries incidence and oral health in general.