Thesiss

Transcription factors (TFs) confer specificity to transcriptional regulation by binding specific DNA sequences and ultimately affecting the ability of RNA polymerase to transcribe a locus. The C2H2 zinc finger proteins (C2H2 ZFPs) are a TF class with the unique ability to divers…

Short Interspersed Nuclear Elements (SINEs) are non-autonomous mobile elements present in eukaryotic genomes. SINEs are mobilized in the form of a transcribed RNA intermediate in a `copy and paste’ process referred to as retrotransposition, by making use of the enzymes encoded b…