Thesiss

m-Estimation represents a broad class of estimators, including least-squares and maximum likelihood, and is a widely used tool for statistical inference. Its successful application however, often requires negotiating physical resources for desired levels of accuracy. These limit…

A phylogenetic tree represents the evolutionary relationships among a set of organisms. Due to several biological processes, the evolutionary histories of the parts of the genome, called gene trees, might not agree with each other, or with the evolution of the species from which…

Bacterial cells during many cell division cycles accumulate spontaneous mutations, which result in the birth of novel clones – cells that carry identical set of mutations. As a result of this clonal expansion, an evolving bacterial population has different clonal composition ove…