RNP-Based Control Systems for Genetic Circuits in Synthetic Biology Beyond CRISPR -- Computational Design of RNA Toehold-Mediated Translation Activators -- Design of RNA-Based Translational Repressors -- Design of Ribocomputing Devices for Complex Cellular Logic -- Computational…
This collection explores the latest advances in riboregulators, such as RNA-only systems and ribonucleoprotein systems, and provides detailed techniques to study, evolve, and design them. Beginning with a set of chapters focused on the design and application of small RNA (sRNA) …
<I> RNA Modification</i> provides a useful examination of the science and its role in biological regulation, the current frontier of life science research, and includes various RNA modications and their role in gene expression. It represents the most up-to-date knowledge and pro…
"RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting, and methods to minimize siRNAâ€TMs unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer, and the p…
The objective of this ""CTMI"" volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine …
The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA re…
The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA re…